TLK286 in Combination With Paraplatin (Carboplatin) in Recurrent Ovarian Cancer
NCT00051948 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2011-07-25
Summary
This is a dose-ranging, open label, Phase 1-2a study of TLK286 in combination with Paraplatin (carboplatin) in patients with recurrent ovarian cancer.
Conditions
- Ovarian Neoplasms
Interventions
- DRUG
-
TLK286
Sponsors & Collaborators
-
Telik
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-01-31
- Primary Completion
- 2005-01-31
- Completion
- 2005-01-31
Countries
- United States
Study Locations
More Related Trials
-
Paclitaxel in Treating Patients With Recurrent or Progressive Advanced Ovarian Cancer
NCT00002928 ·Status: COMPLETED ·Phase: PHASE2
-
TLK286 (Telcyta) vs. Doxil/Caelyx or Hycamtin in Platinum Refractory or Resistant Ovarian Cancer
NCT00057720 ·Status: COMPLETED ·Phase: PHASE3
-
Taxol/ Carboplatin as First Line Therapy in Patients With Epithelial Ovarian Cancer
NCT00170664 ·Status: COMPLETED ·Phase: PHASE2
-
Study of AMG 386 in Combination With Paclitaxel and Carboplatin in Subjects With Ovarian Cancer
NCT01253681 ·Status: COMPLETED ·Phase: PHASE1
-
Carboplatin Taxol Avastin in Ovarian Cancer (OVCA)
NCT00129727 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
NCT00262847 ·Status: COMPLETED ·Phase: PHASE3
-
Pilot Study of Taxol, Carboplatin, and Bevacizumab in Advanced Stage Ovarian Carcinoma Patients
NCT00127920 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy Study of Nuc-1031 and Carboplatin Combination to Treat Recurrent Ovarian Cancer
NCT02303912 ·Status: COMPLETED ·Phase: PHASE1
-
Abraxane Plus Carboplatin for Recurrent Platinum-Sensitive Ovarian Cancer
NCT00466986 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 3 Randomized Study of Telcyta + Doxorubicin Versus Doxorubicin in Platinum Refractory or Resistant Ovarian Cancer
NCT00350948 ·Status: TERMINATED ·Phase: PHASE3
-
Study of Ombrabulin in Patients With Platinum-Sensitive Recurrent Ovarian Cancer Treated With Carboplatin/Paclitaxel
NCT01332656 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating Talazoparib in Relapsed Ovarian, Fallopian Tube, and Peritoneal Cancer
NCT02836028 ·Status: WITHDRAWN ·Phase: PHASE2
-
Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer
NCT01081262 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Topotecan Plus Paclitaxel and Carboplatin in the Initial Treatment of Advanced Ovarian and Primary Peritoneal Carcinoma
NCT00193297 ·Status: COMPLETED ·Phase: PHASE2
-
Circulating Tumor DNA Guiding (Olaparib) Lynparza® Treatment in Ovarian Cancer
NCT02822157 ·Status: UNKNOWN ·Phase: PHASE2
-
A Master Protocol Study to Investigate Biomarker-guided Novel Anticancer Agent(s) as Monotherapy or Combination Therapy in Participants With Advanced/Recurrent Ovarian Cancer
NCT07060365 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Study of Intraperitoneal Carboplatin With IV Paclitaxel and Bevacizumab in Untreated Ovarian Cancer
NCT01220154 ·Status: COMPLETED ·Phase: PHASE1
-
Sorafenib With or Without Paclitaxel and Carboplatin in Treating Patients With Recurrent Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
NCT00096200 ·Status: COMPLETED ·Phase: PHASE2
-
A Study LY2228820 for Recurrent Ovarian Cancer
NCT01663857 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)
NCT00889382 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT02713386 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Paclitaxel, Bevacizumab And Adjuvant Intraperitoneal Carboplatin in Treating Patients Who Had Initial Debulking Surgery for Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
NCT00079430 ·Status: COMPLETED ·Phase: PHASE1
-
First-Line Treatment of Bevacizumab, Carboplatin, and Paclitaxel in Treating Participants With Stage III-IV Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
NCT01097746 ·Status: COMPLETED ·Phase: PHASE2
-
Anti-programmed Cell Death-1 Ligand 1 (aPDL-1) Antibody Atezolizumab, Bevacizumab and Acetylsalicylic Acid in Recurrent Platinum Resistant Ovarian Cancer
NCT02659384 ·Status: COMPLETED ·Phase: PHASE2
-
Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
NCT01167712 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3