Imatinib Mesylate in Treating Patients With Recurrent Meningioma
NCT00045734 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 23
Last updated 2017-05-15
Summary
Phase II trial to study the effectiveness of imatinib mesylate in treating patients who have recurrent meningioma. Imatinib mesylate may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth
Conditions
- Adult Grade I Meningioma
- Adult Grade II Meningioma
- Adult Grade III Meningioma
- Adult Meningeal Hemangiopericytoma
- Adult Meningioma
- Recurrent Adult Brain Tumor
Interventions
- DRUG
-
imatinib mesylate
Given orally
- OTHER
-
laboratory biomarker analysis
Correlative studies
- OTHER
-
pharmacological study
Correlative studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Patrick Wen, MD · North American Brain Tumor Consortium
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-02-28
- Primary Completion
- 2009-12-31
- Completion
- 2009-12-31
Countries
- United States
Study Locations
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