Combination Chemotherapy in Treating Patients With Chronic Lymphocytic Leukemia or Lymphocytic Lymphoma
NCT00045513 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL
Last updated 2015-07-23
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
PURPOSE: Phase I/II trial to study the effectiveness of combining UCN-01 with fludarabine in treating patients who have relapsed or refractory chronic lymphocytic leukemia or lymphocytic lymphoma.
Conditions
Interventions
- DRUG
-
7-hydroxystaurosporine
- DRUG
-
fludarabine phosphate
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University Health Network, Toronto
lead OTHER
Principal Investigators
-
Michael R. Crump, MD, FRCPC · Princess Margaret Hospital, Canada
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-06-30
- Primary Completion
- 2003-12-31
Countries
- Canada
Study Locations
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