Imatinib Mesylate in Treating Patients With Metastatic Breast Cancer
NCT00045188 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2013-01-23
Summary
Phase II trial to study the effectiveness of imatinib mesylate in treating patients who have metastatic breast cancer. Imatinib mesylate may stop the growth of cancer by blocking the enzymes necessary for tumor cell growth
Conditions
- Male Breast Cancer
- Recurrent Breast Cancer
- Stage IV Breast Cancer
Interventions
- DRUG
-
imatinib mesylate
Given PO
- OTHER
-
laboratory biomarker analysis
Optional correlative studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Massimo Cristofanilli · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-08-31
- Primary Completion
- 2004-07-31
Countries
- United States
Study Locations
More Related Trials
-
Irinotecan in Treating Patients With Refractory Metastatic Breast Cancer
NCT00003351 ·Status: COMPLETED ·Phase: PHASE2
-
Study Of Ispinesib In Subjects With Breast Cancer
NCT00089973 ·Status: COMPLETED ·Phase: PHASE2
-
Eribulin Mesylate in Treating Patients With Previously Treated Metastatic Breast Cancer
NCT01908101 ·Status: COMPLETED ·Phase: PHASE2
-
Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer
NCT03101748 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Study of a Novel Indibulin Dosing Schedule for the Treatment of Metastatic Breast Cancer
NCT01113970 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Real-world Study of Inetetamab for First-line Treatment of MBC
NCT05980208 ·Status: NOT_YET_RECRUITING
-
Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
NCT05919108 ·Status: RECRUITING ·Phase: PHASE2
-
Oral Drug Study In Women With Refractory Metastatic Breast Cancer After First-line or Second-line Herceptin.
NCT00051103 ·Status: COMPLETED ·Phase: PHASE2
-
Sunitinib Malate and Exemestane in Treating Postmenopausal Women With Breast Cancer
NCT00931450 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Trial for HER2 Positive Breast Cancer Patients With Metastatic Disease
NCT00191373 ·Status: COMPLETED ·Phase: PHASE2
-
Capecitabine in Treating Patients With Metastatic Breast Cancer
NCT00274768 ·Status: COMPLETED ·Phase: PHASE2
-
A Dose-Escalation Study Evaluating the Combination of Trastuzumab Emtansine (T-DM1) With Neratinib in Women With Metastatic HER2-Positive Breast Cancer
NCT02236000 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Famitinib Malate in HER2-negative Metastatic Breast Cancer
NCT01653574 ·Status: COMPLETED ·Phase: PHASE2
-
Tipifarnib and Gemcitabine Hydrochloride in Treating Women With Metastatic Breast Cancer
NCT00100750 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Randomized Phase II Study Of Eribulin Mesylate With or Without Pembrolizumab For Metastatic Hormone Receptor Positive Breast Cancer
NCT03051659 ·Status: COMPLETED ·Phase: PHASE2
-
S0622, Dasatinib in Treating Patients With Stage IV Breast Cancer That Has Spread to the Bone
NCT00410813 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy Study of Gemcitabine-Paclitaxel to Treat Metastatic Breast Cancer
NCT00316199 ·Status: COMPLETED ·Phase: PHASE2
-
Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast Cancer
NCT03853707 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Irinotecan and Capecitabine in Treating Women With Advanced Breast Cancer
NCT00083148 ·Status: COMPLETED ·Phase: PHASE1
-
Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the Body
NCT05198843 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Trastuzumab and Erlotinib as First-Line Therapy in Treating Women With Metastatic Breast Cancer Associated With HER2/Neu Overexpression
NCT00033514 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Inetetamab Combined With Anti-PD-1 Monoclonal Antibody and Albumin-Bound Paclitaxel for HER2+ Metastatic Breast Cancer
NCT05291910 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Tivantinib in Treating Patients With Recurrent or Metastatic Breast Cancer
NCT01575522 ·Status: COMPLETED ·Phase: PHASE2
-
Management of Metastatic Breast Cancer in Frail Patients
NCT00005614 ·Status: WITHDRAWN ·Phase: PHASE2
-
DZD1516 in Combination With Trastuzumab and Capecitabine, or in Combination With T-DM1, in Patients With Metastatic HER2 Positive Breast Cancer
NCT04509596 ·Status: COMPLETED ·Phase: PHASE1