Lorazepam-Induced Toxicity in the Aged
NCT00044642 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2013-12-06
Summary
This study will compare the effects of an acute dose of lorazepam to a placebo in elderly patients with generalized anxiety disorder (GAD).
Conditions
- Anxiety Disorders
- Generalized Anxiety Disorder
Interventions
- DRUG
-
Lorazepam
Sponsors & Collaborators
-
National Institute of Mental Health (NIMH)
collaborator NIH -
Nathan Kline Institute for Psychiatric Research
lead OTHER
Principal Investigators
-
Nunzio Pomara, MD · Nathan S. Kline Institute and New York University School of Medicine
Study Design
- Allocation
- RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2000-12-31
- Completion
- 2007-07-31
Countries
- United States
Study Locations
More Related Trials
-
Pharmacovigilance in Gerontopsychiatric Patients
NCT02374567 ·Status: TERMINATED ·Phase: PHASE3
-
Use of Benzodiazepines and Z Drugs in the Elderly
NCT01920581 ·Status: UNKNOWN
-
Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug Users
NCT03657355 ·Status: COMPLETED ·Phase: PHASE1
-
Oral Remimazolam With and Without Alcohol in Healthy Female Subjects
NCT04113343 ·Status: COMPLETED ·Phase: PHASE1
-
Clonidine vs. Dexmedetomidine in Agitated Delirium in Intensive Care Patients
NCT04758936 ·Status: UNKNOWN ·Phase: PHASE4
-
Relation Between Psychoactive Drugs Overdosage and Severity of Falls in Elderly People
NCT05991037 ·Status: RECRUITING ·Phase: NA
-
Abuse Potential of Single Doses of Lorcaserin in Healthy Recreational Polydrug Users
NCT00828659 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Abuse Potential of Lasmiditan in Participants Who Are Recreational Drug Users
NCT03286218 ·Status: COMPLETED ·Phase: PHASE1
-
Correlation Between Immune Metabolism in Patients With Benzodiazepine Poisoning and Patients'Mental Disorders
NCT05184959 ·Status: UNKNOWN
-
Staccato Alprazolam Abuse Liability
NCT00603980 ·Status: COMPLETED ·Phase: PHASE1
-
A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room
NCT00457366 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects
NCT05964647 ·Status: COMPLETED ·Phase: PHASE1
-
Psychopharmacological Treatment of Emotional Distress
NCT06133114 ·Status: RECRUITING ·Phase: PHASE4
-
Multimodal Educative Data Feedback for Deprescribing BZD and Related Drugs in Outpatients: a Cluster RCT
NCT05859555 ·Status: COMPLETED ·Phase: NA
-
Acute Agitation in Emergency Psychiatry
NCT06752616 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Benzodiazepines for the Reduction of Distress and Pain During and After Emergency Department Care
NCT03756038 ·Status: TERMINATED ·Phase: PHASE2
-
Prescription of Benzodiazepines by General Practitioners: Characteristics of Prescribing Trend and Implementation of an Online Educational Program
NCT04925596 ·Status: COMPLETED ·Phase: NA
-
Rapid Benzodiazepine Detoxification Using Flumazenil - 1
NCT00000246 ·Status: COMPLETED ·Phase: PHASE2
-
Haloperidol Prophylaxis in Older Emergency Department Patients
NCT01530308 ·Status: COMPLETED ·Phase: PHASE4
-
GABA Pathways in Autism Spectrum Disorder (ASD)
NCT03678129 ·Status: COMPLETED ·Phase: NA
-
Physiological, Behavioral and Subjective Effects of Drugs (GHB)
NCT00058955 ·Status: COMPLETED ·Phase: PHASE1
-
Opiates and Benzodiazepines on Driving
NCT03447353 ·Status: COMPLETED ·Phase: PHASE4
-
pRophylactic halopEriDol Use for Delirium in iCu patiEnts With a High Risk for Delirium
NCT01785290 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of The Abuse Liability Potential of RO4917838 in Recreational Drug Users
NCT01438749 ·Status: COMPLETED ·Phase: PHASE1
-
Placebo Effects on Blood Pressure Induced by Expectancy Manipulation
NCT00937196 ·Status: COMPLETED ·Phase: NA