A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies
NCT00043199 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2005-06-24
Summary
To determine the rate of response and duration of reponse following therapy with Aroplatin in subjects with advanced colorectal cancer resistant to standard therapies. Secondary objectives are to determine safety and tolerability of the Aroplatin therapy.
Conditions
- Colorectal Neoplasms
Interventions
- DRUG
-
Aroplatin (Liposomal NDDP, L-NDDP)
Sponsors & Collaborators
-
Aronex Pharmaceuticals
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
More Related Trials
-
Assessing Safety of NIPOX in Peritoneal Carcinomatosis of CRC
NCT03253133 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate Progression Free Survival in Cancer Patients With Advanced Colorectal Carcinoma With AMT2003
NCT00405561 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer.
NCT00056459 ·Status: COMPLETED ·Phase: PHASE3
-
Fluorouracil and Leucovorin With or Without Oxaliplatin in Treating Patients With Recurrent Metastatic Colorectal Cancer
NCT00016198 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of FOLFOX+Bevacizumab in Combination With Irinotecan in the Treatment of Metastatic Colorectal Cancer
NCT01321957 ·Status: COMPLETED ·Phase: PHASE2
-
Impact of FOLFIRINOX Chemotherapy in IV Stage Colorectal Cancer Patients Previously Exposed to Irinotecan, Fluoropyrimidine and Oxaliplatin
NCT05354817 ·Status: UNKNOWN ·Phase: PHASE2
-
A Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal Cancer
NCT00040391 ·Status: TERMINATED ·Phase: PHASE2
-
Safety of Orectalip® (Oxaliplatin) as Adjuvant Treatment for High-risk Stage-Ⅱ Colorectal Cancer
NCT02284529 ·Status: COMPLETED ·Phase: PHASE4
-
Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid Tumors
NCT00138177 ·Status: COMPLETED ·Phase: PHASE1
-
Oxaliplatin, 5-FU and Leucovorin in Combination With Oral Capecitabine for Metastatic Colorectal Cancer
NCT00205322 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan With or Without Panitumumab or Cyclosporine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Fluorouracil
NCT00389870 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Colorectal Cancer
NCT00039208 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal Carcinoma (Cancer), Other Refractory Carcinoma, or Metastatic Adenoma (Cancer) of Unknown Primary Origin
NCT00004005 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer
NCT00069121 ·Status: COMPLETED ·Phase: PHASE3
-
Trial Evaluating 3-year Disease Free Survival in Patients With Locally Advanced Rectal Cancer Treated With Chemoradiation Plus Induction or Consolidation Chemotherapy and Total Mesorectal Excision or Non-operative Management
NCT02008656 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery
NCT01150045 ·Status: COMPLETED ·Phase: PHASE3
-
Oxaliplatin in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer
NCT00040820 ·Status: COMPLETED ·Phase: NA
-
Irinotecan/Oxaliplatin/5-Fluorouracil/Leucovorin/Cetuximab As First Line Treatment In Colorectal Cancer
NCT00689624 ·Status: COMPLETED ·Phase: PHASE2
-
AVELUMAB and CETUXIMAB and mFOLFOXIRI as Initial Therapy for Unresectable Metastatic Colorectal Cancer Patients
NCT04513951 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil, Oxaliplatin, and Bevacizumab in Patients With Advanced Colorectal Cancer
NCT03750786 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer Previously Treated With Irinotecan
NCT00016978 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan, Fluorouracil, Leucovorin, and Oxaliplatin as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer
NCT00080951 ·Status: COMPLETED ·Phase: PHASE2
-
Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer
NCT03337087 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Preoperative Radiotherapy and Chemotherapy in Patients With Locally Advanced Rectal Cancer
NCT01013805 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of Oxaliplatin and 5-fluorouracil Followed by FUDR for Unresectable Colorectal Liver Metastases
NCT00557557 ·Status: COMPLETED ·Phase: PHASE1