MedTrace Logo

Radiation Therapy With or Without Carbogen and Niacinamide in Treating Patients With Bladder Cancer

NCT00033436 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 330

Last updated 2013-09-20

No results posted yet for this study

Summary

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as carbogen and niacinamide may make tumor cells more sensitive to radiation therapy. It is not yet known whether radiation therapy is more effective with or without carbogen and niacinamide in treating patients who have bladder cancer.

PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without carbogen and niacinamide in treating patients who have locally advanced bladder cancer.

Conditions

Interventions

DIETARY_SUPPLEMENT

niacinamide

DRUG

carbogen

RADIATION

radiation therapy

Sponsors & Collaborators

  • Mount Vernon Cancer Centre at Mount Vernon Hospital

    lead OTHER

Principal Investigators

  • Peter J. Hoskin, MD · Mount Vernon Cancer Centre at Mount Vernon Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2000-10-31
Completion
2008-11-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00033436 on ClinicalTrials.gov