Erlotinib in Treating Patients With Locally Advanced or Metastatic Breast Cancer
NCT00030537 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-19
Summary
RATIONALE: Biological therapies such as erlotinib may interfere with the growth of tumor cells and slow the growth of the tumor.
PURPOSE: Phase II trial to study the effectiveness of erlotinib in treating patients who have locally advanced or metastatic breast cancer.
Conditions
Interventions
- DRUG
-
erlotinib hydrochloride
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Antoinette R. Tan, MD · National Cancer Institute (NCI)
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-11-30
- Completion
- 2003-03-31
Countries
- United States
Study Locations
More Related Trials
-
Lapatinib Combined With Paclitaxel For Patients With First-Line ErbB2-Amplified Metastatic Breast Cancer
NCT00356811 ·Status: COMPLETED ·Phase: PHASE2
-
Palbociclib in Estrogen Receptor Positive (ER+) Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer
NCT03709082 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of Biweekly Regimen of Eribulin Versus a Standard Regimen for the Treatment of Locally Recurrent or Metastatic HER2-negative Breast Cancer: a Multicenter, Randomized, Open-label, Phase III Trial
NCT06857305 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE3
-
A Trial of Erlotinib + Radiotherapy for Cutaneous Squamous Cell Carcinoma
NCT00369512 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of a New Drug Combination, Copanlisib and Fulvestrant, in Advanced Breast Cancer
NCT03803761 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
A Real-world Clinical Study of Pyrotinib Maleate Tablets in the Treatment of Breast Cancer Patients With Positive Her-2
NCT03908749 ·Status: UNKNOWN
-
Palbociclib in Combination With Adjuvant Endocrine Therapy for Hormone Receptor Positive, HER2 Negative Invasive Breast Cancer
NCT02040857 ·Status: COMPLETED ·Phase: PHASE2
-
Adjuvant Erlotinib After Completing Chemoradiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and Neck
NCT00079053 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase II Trial Testing Oral Administration of Lucitanib in Patients With Fibroblast Growth Factor Receptor (FGFR)1-amplified or Non-amplified Estrogen Receptor Positive Metastatic Breast Cancer
NCT02053636 ·Status: COMPLETED ·Phase: PHASE2
-
BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer
NCT06756932 ·Status: RECRUITING ·Phase: PHASE1
-
A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer
NCT07054190 ·Status: RECRUITING ·Phase: PHASE2
-
Irinotecan for Advanced and Metastatic Breast Cancer
NCT03562390 ·Status: UNKNOWN ·Phase: PHASE2
-
Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
NCT05455619 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Fulvestrant, Palbociclib and Erdafitinib in ER+/HER2-/FGFR-amplified Metastatic Breast Cancer
NCT03238196 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer
NCT05508906 ·Status: RECRUITING ·Phase: PHASE1
-
Durvalumab, With Olaparib and Fulvestrant in Advanced ER+, HER2- Breast Cancer Patients.
NCT04053322 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
G1T48, an Oral SERD, Alone and in Combination With Palbociclib in ER-Positive, HER2-Negative Advanced Breast Cancer
NCT03455270 ·Status: COMPLETED ·Phase: PHASE1
-
Eribulin Mesylate or Paclitaxel as First- or Second-Line Therapy in Treating Patients With Recurrent Stage IIIC-IV Breast Cancer
NCT02037529 ·Status: SUSPENDED ·Phase: PHASE3
-
A First-in-Human Study of D-0502 Alone and in Combination With Palbociclib in Women With Advanced or Metastatic ER-Positive and HER2-Negative Breast Cancer
NCT03471663 ·Status: COMPLETED ·Phase: PHASE1
-
Pyrotinib, Dalpiciclib(SHR6390) and Endocrine Therapy in Subjects With Dual-receptor Positive(ER+/HER2+) Advanced Breast Cancer
NCT03772353 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase 2 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of YL202 in Patients With BC
NCT06439771 ·Status: RECRUITING ·Phase: PHASE2
-
This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer
NCT03099174 ·Status: COMPLETED ·Phase: PHASE1
-
Patient Characteristics, Treatment Patterns, and Clinical Outcomes in Patients Diagnosed With HR+/HER2 Advanced/Metastatic Breast Cancer on Palbociclib + Aromatase Inhibitor (AI) Combination Therapy
NCT04394247 ·Status: COMPLETED
-
Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer
NCT00680758 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment
NCT06105632 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2