Celecoxib in Preventing Skin Cancer
NCT00025051 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-03-22
Summary
RATIONALE: Celecoxib may be effective in preventing skin cancer by decreasing redness caused by exposure to ultraviolet light and changing potential skin cancer biomarkers. It is not yet known whether celecoxib is more effective than a placebo in preventing skin cancer.
PURPOSE: Randomized phase II trial to study the effectiveness of celecoxib in preventing skin cancer in participants exposed to ultraviolet light.
Conditions
- Non-melanomatous Skin Cancer
Interventions
- DRUG
-
celecoxib
- PROCEDURE
-
anti-cytokine therapy
- PROCEDURE
-
antiangiogenesis therapy
- PROCEDURE
-
biological therapy
- PROCEDURE
-
cancer prevention intervention
- PROCEDURE
-
chemoprevention of cancer
- PROCEDURE
-
growth factor antagonist therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
David R. Bickers, MD · Herbert Irving Comprehensive Cancer Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
Eligibility
- Min Age
- 20 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
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