Antiviral Therapy in Treating Patients With Kaposi's Sarcoma With or Without HIV Infection
NCT00019240 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-20
Summary
RATIONALE: Herpesvirus is found in Kaposi's sarcoma lesions in most patients; it is therefore possible that the herpesvirus has a role in causing Kaposi's sarcoma. Cidofovir is an antiviral drug that acts against many types of herpesvirus, and may be an effective treatment for Kaposi's sarcoma.
PURPOSE: Phase II trial to study the effectiveness of cidofovir in treating patients with Kaposi's sarcoma with or without HIV infection.
Conditions
- Sarcoma
Interventions
- DRUG
-
cidofovir
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Robert Yarchoan, MD · National Cancer Institute (NCI)
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1996-11-30
- Completion
- 2004-04-30
Countries
- United States
Study Locations
More Related Trials
-
Efficacy and Safety Trial of Topical Resiquimod Gel (0.06%) in Patients With Nodular Basal Cell Carcinoma
NCT01808950 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Bevacizumab Versus Cidofovir for the Treatment of Recurrent Respiratory Papillomatosis
NCT02555800 ·Status: UNKNOWN ·Phase: PHASE2
-
M7824 in Subjects With HPV Associated Malignancies
NCT03427411 ·Status: COMPLETED ·Phase: PHASE2
-
Carrageenan-Containing Gel in Reducing the Rate of HPV Infection in Healthy Participants
NCT02382419 ·Status: WITHDRAWN ·Phase: PHASE2
-
Papilloma Virus Vaccine Therapy in Treating Young Patients With Recurrent Papilloma of the Larynx
NCT00002454 ·Status: UNKNOWN ·Phase: PHASE2
-
Avelumab for People With Recurrent Respiratory Papillomatosis
NCT02859454 ·Status: COMPLETED ·Phase: PHASE2
-
Comparing CO2 Laser and Electrosurgical Treatments for Perianal Condyloma
NCT06166290 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Hespecta Vaccination in HPV+ Tumors or Malignant Lesions
NCT02821494 ·Status: COMPLETED ·Phase: PHASE1
-
Topical Ascorbic Acid for Treatment of Squamous Cell Skin Cancer
NCT05932511 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Twelve Week Safety and Efficacy Study With a Topical Gel to Treat Common Warts in Adults
NCT00114920 ·Status: COMPLETED ·Phase: PHASE2
-
Cnidium Monnieri Detoxification Formula for Persistent High-risk Human Papillomavirus Infection of Cervix.
NCT06705322 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis
NCT04724980 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)
NCT05026138 ·Status: RECRUITING
-
On the Impact of Therapeutic Tumor Necrosis Factor-alpha Inhibition on Anogenital Human Papillomavirus Infection
NCT02376478 ·Status: COMPLETED
-
Vismodegib for Treatment of Basal Cell Carcinoma
NCT01543581 ·Status: COMPLETED ·Phase: PHASE2
-
A Randomized Study to Evaluate the Safety and Efficacy of Various Doses of STP705 in Subjects With Hypertrophic Scar
NCT02956317 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase II Study of Treatment for HPV16+ ASC-US, ASC-H and LSIL
NCT03911076 ·Status: TERMINATED ·Phase: PHASE2
-
Topical NVN1000 for the Treatment of External Genital and Perianal Warts
NCT02462187 ·Status: COMPLETED ·Phase: PHASE2
-
A Study HB-201 in Patients With Newly Diagnosed HPV16+ Oropharynx or Locally Advanced Cervical Cancer
NCT04630353 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)
NCT03721978 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Topical Applications of AP611074 5% Gel for up to 16 Weeks in Condyloma Patients
NCT02724254 ·Status: COMPLETED ·Phase: PHASE2
-
CyPep-1 in Cutaneous Warts
NCT03846648 ·Status: COMPLETED ·Phase: PHASE1
-
AV2 Antiviral Spray Versus Placebo in Human Papillomavirus Cervix Infections
NCT01654822 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Efficacy Study of Topical Ranpirnase to Treat Genital Warts (HPV)
NCT02535104 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)
NCT03185013 ·Status: COMPLETED ·Phase: PHASE3