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Evaluation and Treatment of Patients With Epilepsy

NCT00013845 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 1278

Last updated 2019-12-12

No results posted yet for this study

Summary

This protocol has three purposes: 1) to screen patients with seizures for participation in research studies of NINDS s Clinical Epilepsy Section (CES), 2) to follow the natural course of seizure disorders, and 3) to train CES fellows in evaluating and treating epilepsy. Only standard diagnostic tests and treatments will be used in this study.

Patients of any age with seizures who are referred to CES may participate in this study. At the end of the study, patients may be discharged to the care of their referring physician, offered participation in another NINDS research protocol, or followed for teaching purposes.

Participants will undergo standard diagnostic procedures used to determine the type of their seizures, what part of the brain they are coming from, what is causing them, and whether standard drug treatments can help them. These may include some or all of the following:

* Physical and neurological examination
* Neuropsychological tests tests of learning and memory
* Electroencephalography (EEG) brain wave recording
* Evoked potentials tests of nerve reactions to lights and sounds
* Polysomnography simultaneous recordings of brain waves, breathing and eye movements
* Video-EEG monitoring simultaneous recording of seizures using a video camera and brain waves
* Video-EEG monitoring with extra electrodes to record muscle activity, breathing and eye movements for analyzing sleep patterns
* Imaging studies, such as magnetic resonance imaging (MRI) and positron emission tomography (PET) scans to examine the structure and function of the brain
* Frequent blood tests to measure blood levels of anti-seizure drugs

Conditions

Sponsors & Collaborators

  • National Institute of Neurological Disorders and Stroke (NINDS)

    lead NIH

Principal Investigators

  • Sara K Inati, M.D. · National Institute of Neurological Disorders and Stroke (NINDS)

Eligibility

Min Age
2 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2001-05-01
Completion
2018-06-26

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00013845 on ClinicalTrials.gov