Interleukin-2 in Treating Children Who Have Undergone Bone Marrow Transplantation for Acute Myeloid Leukemia
NCT00009698 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 1
Last updated 2013-06-28
Summary
RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill more cancer cells.
PURPOSE: Phase I trial to study the effectiveness of interleukin-2 in treating children who have undergone bone marrow transplantation for acute myeloid leukemia.
Conditions
Interventions
- BIOLOGICAL
-
aldesleukin
Given SQ and IV
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Children's Oncology Group
lead NETWORK
Principal Investigators
-
Kimo C. Stine, MD · Arkansas Children's Hospital at the University of Arkansas for Medical Sciences
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Max Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-03-31
- Primary Completion
- 2001-06-30
- Completion
- 2005-09-30
Countries
- United States
- Australia
- Canada
- Netherlands
- Puerto Rico
- Switzerland
Study Locations
More Related Trials
-
Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
NCT00002798 ·Status: COMPLETED ·Phase: PHASE3
-
Allogeneic Cytokine-induced Killer Immunotherapy for Relapse After Allogeneic Marrow Transplant for Haematological Malignancies
NCT00460694 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy Followed by Melphalan and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Acute Myeloid Leukemia
NCT00004056 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia
NCT00003436 ·Status: COMPLETED ·Phase: PHASE3
-
Therapeutic Allogeneic Lymphocytes and Aldesleukin in Treating Patients With High-Risk or Recurrent Myeloid Leukemia After Undergoing Donor Stem Cell Transplant
NCT00052598 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Study of (Interleukin-12) IL-12 in Patients With Acute Myelogenous Leukemia (AML)
NCT02483312 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Interleukin-2 Plus Histamine Dihydrochloride in Treating Patients With Acute Myeloid Leukemia
NCT00003991 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Children With Relapsed Acute Lymphocytic Leukemia
NCT00002499 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia
NCT00002658 ·Status: UNKNOWN ·Phase: PHASE3
-
Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia
NCT00005945 ·Status: COMPLETED ·Phase: PHASE3
-
Interleukin-21 (IL-21)- Expanded Natural Killer Cells for Induction of Acute Myeloid Leukemia
NCT02809092 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT00005596 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome
NCT00002517 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy, Interleukin-2, and Peripheral Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia
NCT00004128 ·Status: UNKNOWN ·Phase: PHASE3
-
A Phase I Single-arm Clinical Study of Donor NK Cells Infusion Combined with Low-dose Interleukin-2 in the Treatment of Acute Myeloid Leukemia Relapse After Allogeneic Hematopoietic Stem Cell Transplantation.
NCT06641648 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Personalized Targeted Preparative Regimen Before T-depleted Allogeneic HSCT in Children With Chemoresistent Acute Leukemias
NCT04000698 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy Plus PSC 833 Followed by Interleukin-2 in Treating Patients With Acute Myelogenous Leukemia
NCT00002925 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy With or Without PSC 833, Peripheral Stem Cell Transplantation, and/or Interleukin-2 in Treating Patients With Acute Myeloid Leukemia
NCT00006363 ·Status: COMPLETED ·Phase: PHASE3
-
Trial of Daily Pulse Interleukin-2 With Famotidine in Acute Myelogenous Leukemia
NCT01289678 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
NCT00005603 ·Status: COMPLETED ·Phase: PHASE3
-
Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia
NCT01076569 ·Status: COMPLETED
-
Treatment of Children and Adolescents With Refractory or Relapsed Acute Myeloid Leukemia
NCT00186966 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia
NCT00372593 ·Status: COMPLETED ·Phase: PHASE3
-
Lenalidomide in Treating Patients With High Risk Acute Myeloid Leukemia in Remission
NCT02126553 ·Status: COMPLETED ·Phase: PHASE2
-
High Dose Ara-C (HDAC) and Interleukin-2 (IL-2) for Patients With Acute Myelogenous Leukemia (AML)
NCT00136448 ·Status: COMPLETED ·Phase: PHASE2