Zidovudine Plus Interleukin-2 and Ganciclovir in Treating Patients With AIDS-Related Primary Central Nervous System Lymphoma
NCT00006264 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2016-02-03
Summary
RATIONALE: Antiviral drugs such as zidovudine and ganciclovir act against viruses and may be an effective treatment for HIV. Interleukin-2 may stimulate a person's white blood cells to kill lymphoma cells. Combining these treatments may be effective in treating AIDS-related primary central nervous system lymphoma.
PURPOSE: Phase II trial to study the effectiveness of combining zidovudine, ganciclovir, and interleukin-2 in treating patients who have AIDS-related primary central nervous system lymphoma.
Conditions
Interventions
- BIOLOGICAL
-
aldesleukin
- DRUG
-
ganciclovir
- DRUG
-
zidovudine
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
AIDS Malignancy Consortium
lead NETWORK
Principal Investigators
-
William J. Harrington, MD · University of Miami Sylvester Comprehensive Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-07-31
- Primary Completion
- 2003-03-31
- Completion
- 2003-07-31
Countries
- United States
Study Locations
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