Ursodiol-Methotrexate for Primary Biliary Cirrhosis
NCT00006168 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL
Last updated 2010-01-13
Summary
The major thrust is to determine whether treatment of patients with Primary Biliary Cirrhosis (PBC) with Ursodiol (Ursodeoxycholic Acid-UDCA) plus methotrexate (MTX) is more effective than treatment with UDCA alone.
Conditions
- Liver Cirrhosis, Biliary
Interventions
- DRUG
-
Methotrexate
Sponsors & Collaborators
-
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
lead NIH
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
Eligibility
- Min Age
- 20 Years
- Max Age
- 69 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1994-01-31
- Completion
- 2004-03-31
Countries
- United States
Study Locations
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