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The Effect of Estrogen and Progesterone Levels on Knee and Ankle Joint Laxity

NCT00005923 · Status: UNKNOWN · Type: OBSERVATIONAL

Last updated 2005-06-24

No results posted yet for this study

Summary

The proposed research is an observational study designed to compare estrogen and progesterone serum levels with knee and ankle joint laxity, and muscle reaction time as a measure of neuromuscular function. Three groups of women athletes with differing estrogen and progesterone profiles (normal menstrual cycles, amenorrheic, and exogenous estrogen supplementation) and one control group (male collegiate athletes) will be used to compare differences in joint laxity and neuromuscular function. Blood levels of estrogen and progesterone will be measured at four time points across the menstrual cycle. Joint laxity and muscle reaction time will also be measured at each of these points. The investigator hypothesizes that knee and ankle joint laxity and muscle reaction time will significantly increase with increasing estrogen and progesterone levels.

Conditions

  • Healthy

Sponsors & Collaborators

  • National Center for Research Resources (NCRR)

    lead NIH

Eligibility

Min Age
15 Years
Max Age
23 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00005923 on ClinicalTrials.gov