Clinical Interventions in Respiratory Distress Syndrome and Neonatal Lung Injury - SCOR in Lung Biology and Diseases in Infants and Children
NCT00005683 · Status: COMPLETED · Type: OBSERVATIONAL
Last updated 2016-01-15
Summary
To conduct clinical interventions directed at neonatal lung disease and injury, with a focus on infants having surfactant-deficiency or inactivation as a component of pathophysiology. A major emphasis was on the surfactant-deficient Respiratory Distress Syndrome (RDS) of premature infants, and on acute neonatal respiratory failure in term infants with pulmonary edema and potential surfactant inactivation (ARDS-related).
Conditions
- Lung Diseases
- Respiratory Distress Syndrome
- Bronchopulmonary Dysplasia
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH -
University of Rochester
lead OTHER
Eligibility
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1986-12-31
- Completion
- 1997-11-30
More Related Trials
-
Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies
NCT01607216 ·Status: COMPLETED
-
Sustained Lung Inflation With CPAP in Preterm Neonates (SI-CPAP)
NCT03916523 ·Status: COMPLETED ·Phase: NA
-
Physiological Phenotyping of Respiratory Outcomes in Infants Born Premature
NCT03906708 ·Status: ACTIVE_NOT_RECRUITING
-
Antecedents of Bronchopulmonary Dysplasia
NCT00005293 ·Status: COMPLETED
-
Prevention of Neonatal Respiratory Distress Syndrome With Antenatal Steroid Administration
NCT00000563 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure
NCT05849116 ·Status: UNKNOWN
-
Genetic Regulation of Surfactant Deficiency
NCT00828243 ·Status: COMPLETED
-
Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS
NCT01996670 ·Status: COMPLETED
-
Predictive Value of Lung Ultrasound for Respiratory Decompensation in Late Preterm Neonates
NCT07216053 ·Status: RECRUITING
-
The Effect of Standardizing the Definition of a Clinically Significant Cardiopulmonary Event on Length of Stay
NCT03414671 ·Status: COMPLETED
-
Biomarkers and Volumetric Capnography in BPD
NCT02083562 ·Status: COMPLETED
-
Work of Breathing in Premature Infants at Discharge
NCT03682575 ·Status: COMPLETED
-
Aerosolized Surfactant in Neonatal RDS
NCT02294630 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Minimally Invasive Surfactant Therapy Followed by CPAP (MISTCPAP) in Preterm Infants With RDS
NCT01723683 ·Status: UNKNOWN ·Phase: PHASE2
-
Lung Ultrasound to Guide Surfactant Therapy
NCT04330443 ·Status: COMPLETED ·Phase: NA
-
Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
NCT06373289 ·Status: RECRUITING ·Phase: NA
-
Clinical RD (Respiratory Distress) Score for Objective Decision Making for Surfactant Therapy
NCT03273764 ·Status: COMPLETED
-
Recombinant Surfactant Protein D (rfhSP-D) to Prevent Neonatal Chronic Lung Disease
NCT05898633 ·Status: COMPLETED ·Phase: PHASE1
-
Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(NARDS)
NCT04777760 ·Status: RECRUITING
-
Application of Lung Near-Infrared Spectroscopy (NIRS) in Preterm Infants
NCT05961670 ·Status: UNKNOWN
-
Optimal Dose of Surfactant for Preterm Infants With Respiratory Distress Syndrome
NCT04984057 ·Status: UNKNOWN ·Phase: NA
-
Fast Assessment of Surfactant Deficiency in Preterm Infants to Speed up Treatment
NCT05638568 ·Status: WITHDRAWN ·Phase: NA
-
The Effect of Surfactant Dose on Outcomes in Preterm Infants With RDS
NCT03808402 ·Status: COMPLETED
-
Premature Birth and Its Sequelae in Women
NCT00005376 ·Status: COMPLETED
-
Fluid Restriction in Respiratory Distress of the Newborn
NCT03120585 ·Status: COMPLETED ·Phase: NA