Paclitaxel and Bryostatin 1 in Treating Patients With Metastatic Prostate Cancer
NCT00005028 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 46
Last updated 2019-11-04
Summary
Phase II trial to study the effectiveness of combining paclitaxel and bryostatin 1 in treating patients who have metastatic prostate cancer that has not responded to hormone therapy. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
Conditions
Interventions
- DRUG
-
bryostatin 1
- DRUG
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Maryland, Baltimore
lead OTHER
Principal Investigators
-
Arif Hussain, MD · University of Maryland Greenebaum Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-05-31
- Primary Completion
- 2006-07-31
- Completion
- 2006-07-31
Countries
- United States
Study Locations
More Related Trials
-
Paclitaxel Plus Estramustine in Treating Patients With Metastatic Prostate Cancer
NCT00003717 ·Status: UNKNOWN ·Phase: PHASE2
-
Docetaxel, Prednisone, and Vatalanib in Treating Patients With Advanced Prostate Cancer
NCT00293371 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Estramustine, Docetaxel, and Carboplatin in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00005627 ·Status: COMPLETED ·Phase: PHASE1
-
S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer
NCT00028769 ·Status: COMPLETED ·Phase: PHASE2
-
Crizotinib in Combination With Enzalutamide in Metastatic Castration-resistant Prostate Cancer
NCT02207504 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer
NCT00003394 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Paclitaxel, Topotecan, and Estramustine in Treating Patients With Metastatic Hormone-Refractory Prostate Cancer
NCT00084565 ·Status: WITHDRAWN ·Phase: PHASE2
-
Docetaxel, Estramustine, and Exisulind in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00052845 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Plus Filgrastim in Treating Patients With Stage IV Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00005810 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel in Treating Patients With Stage II or Stage III Prostate Cancer
NCT00005096 ·Status: COMPLETED ·Phase: PHASE2
-
Weekly Paclitaxel, Low-Dose Estramustine, and Carboplatin in the Treatment of Hormone Refractory Prostate Carcinoma
NCT00193193 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel and Prednisone in Treating Patients With Hormone-Refractory Metastatic Prostate Cancer
NCT00255606 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00005960 ·Status: UNKNOWN ·Phase: PHASE2
-
Doxorubicin Plus Estramustine in Treating Patients With Metastatic Prostate Cancer
NCT00002721 ·Status: COMPLETED ·Phase: PHASE1
-
CT-2584 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Previous Therapy
NCT00004026 ·Status: TERMINATED ·Phase: PHASE2
-
BMS-275291 in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00040755 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel Plus Estramustine in Treating Patients With Metastatic Prostate Cancer
NCT00002775 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
COMbination of Bipolar Androgen Therapy and Nivolumab
NCT03554317 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate Cancer
NCT04100018 ·Status: COMPLETED ·Phase: PHASE3
-
Docetaxel and Prednisone With or Without Cediranib in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy
NCT00527124 ·Status: TERMINATED ·Phase: PHASE2
-
Enzalutamide and Decitabine in Treating Patients With Metastatic Castration Resistant Prostate Cancer
NCT03709550 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate Cancer
NCT00744497 ·Status: COMPLETED ·Phase: PHASE3
-
Study of AS1404 With Docetaxel in Patients With Hormone Refractory Metastatic Prostate Cancer
NCT00111618 ·Status: COMPLETED ·Phase: PHASE2
-
DHA-Paclitaxel in Treating Patients With Metastatic Prostate Cancer
NCT00024414 ·Status: UNKNOWN ·Phase: PHASE2
-
Docetaxel and Prednisone With or Without Bevacizumab in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
NCT00110214 ·Status: COMPLETED ·Phase: PHASE3