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Study of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis

NCT00004705 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL

Last updated 2015-03-25

No results posted yet for this study

Summary

OBJECTIVES: I. Determine the stability of uridine triphosphate (UTP) and examine the metabolism of exogenous nucleotides on airway epithelial surfaces in patients with cystic fibrosis.

II. Determine the acute safety and efficacy of aerosolized UTP in children with cystic fibrosis.

Conditions

Interventions

DRUG

amiloride

DRUG

uridine

Sponsors & Collaborators

  • University of North Carolina

    collaborator OTHER

  • FDA Office of Orphan Products Development

    lead FED

Principal Investigators

  • Michael R. Knowles · University of North Carolina

Study Design

Purpose
TREATMENT

Eligibility

Min Age
4 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1996-09-30
Completion
1999-01-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00004705 on ClinicalTrials.gov