Phase II Study of the Enzyme Inhibitor NTBC for Tyrosinemia Type I
NCT00004333 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2005-06-24
Summary
OBJECTIVES:
Assess whether 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC) at 0.6 mg/kg per day prevents liver failure in at least 1 patient with tyrosinemia type I.
Conditions
- Tyrosinemia, Type I
Interventions
- DRUG
-
NTBC
Sponsors & Collaborators
- collaborator OTHER
-
National Center for Research Resources (NCRR)
lead NIH
Principal Investigators
-
Jess G. Thoene · University of Michigan
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 0 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1994-11-30
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