MedTrace Logo

Hippocampal Complex Volume and Memory Dysfunction in Cushing's Syndrome

NCT00004326 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2005-06-24

No results posted yet for this study

Summary

OBJECTIVES: I. Evaluate whether chronic hypercortisolemia is specifically toxic to hippocampal cells and causes structural reduction of hippocampal volume in patients with Cushing's syndrome.

II. Determine whether reduced hippocampal volume is associated with specific memory dysfunction.

III. Examine the relationships of adrenal androgen to hippocampal volume and memory dysfunction.

IV. Examine the reversibility of hippocampal structural changes and cognitive dysfunction after cortisol levels are normalized.

Conditions

Sponsors & Collaborators

Principal Investigators

  • Monica N. Starkman · University of Michigan

Eligibility

Min Age
15 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1994-08-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00004326 on ClinicalTrials.gov