Genetic Study of Children With Soft Tissue Sarcoma or Rhabdomyosarcoma
NCT00003793 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 294
Last updated 2014-08-05
Summary
RATIONALE: Determination of genetic markers for soft tissue sarcoma or rhabdomyosarcoma may help doctors identify patients who are at risk for therapy-related leukemia.
PURPOSE: Clinical trial to study genetic testing of children with soft tissue sarcoma or rhabdomyosarcoma to identify children who are at risk of developing leukemia from the chemotherapy used to treat sarcoma.
Conditions
- Leukemia
- Myelodysplastic Syndromes
- Sarcoma
Interventions
- GENETIC
-
clonality analysis
- GENETIC
-
microsatellite instability analysis
- GENETIC
-
mutation analysis
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Children's Oncology Group
lead NETWORK
Principal Investigators
-
Stella M. Davies, MBBS, PhD · Children's Hospital Medical Center, Cincinnati
Eligibility
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-12-31
- Primary Completion
- 2005-12-31
- Completion
- 2007-03-31
Countries
- United States
- Australia
- Canada
Study Locations
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