Interleukin-12 in Treating Women With Metastatic Breast Cancer Who Have Received High-Dose Chemotherapy and Peripheral Stem Cell Transplantation
NCT00003412 · Status: UNKNOWN · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2013-09-17
Summary
RATIONALE: Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a person's white blood cells to kill breast cancer cells.
PURPOSE: Phase I trial to study the effectiveness of interleukin-12 in treating women with metastatic breast cancer who have received high-dose chemotherapy and peripheral stem cell transplantation.
Conditions
Interventions
- BIOLOGICAL
-
recombinant interleukin-12
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Beth Israel Deaconess Medical Center
lead OTHER
Principal Investigators
-
David Avigan, MD · Beth Israel Deaconess Medical Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-06-30
Countries
- United States
Study Locations
More Related Trials
-
BP-C1 in Metastatic Breast Cancer Patients
NCT01861509 ·Status: COMPLETED ·Phase: PHASE1
-
Purged Circulating Tumor Cells (CTCs) From Metastatic Breast Cancer
NCT00429182 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy and Progenitor Cell Transplantation to Treat Inflammatory Breast Cancer
NCT00001507 ·Status: COMPLETED ·Phase: PHASE1
-
Perillyl Alcohol in Treating Patients With Metastatic Breast Cancer
NCT00003219 ·Status: COMPLETED ·Phase: PHASE2
-
Laboratory-Treated T Cells After Second-Line Chemotherapy in Treating Patients With HER2/Neu-Negative Metastatic Breast Cancer
NCT01022138 ·Status: TERMINATED ·Phase: PHASE2
-
Phase II Trial of Weekly or Every 3-week Ixabepilone for Patients With Metastatic Breast Cancer
NCT00593827 ·Status: COMPLETED ·Phase: PHASE2
-
Ex Vivo-Expanded HER2-Specific T Cells and Cyclophosphamide After Vaccine Therapy in Treating Patients With HER2-Positive Stage IV Breast Cancer
NCT01219907 ·Status: WITHDRAWN ·Phase: PHASE1
-
Carboplatin and Bevacizumab for Progressive Breast Cancer Brain Metastases
NCT01004172 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody Plus Chemotherapy in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2
NCT00019812 ·Status: COMPLETED ·Phase: PHASE2
-
High Dose Chemo With Autologous BMT for Treatment of Metastatic Breast Cancer
NCT00584428 ·Status: COMPLETED ·Phase: NA
-
Vaccine Therapy in Treating Women With Metastatic Breast Cancer
NCT00003638 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy and Trastuzumab in Treating Women With Metastatic Breast Cancer
NCT00003612 ·Status: COMPLETED ·Phase: PHASE2
-
Metronomic Therapy in Metastatic Breast Cancer.
NCT01131195 ·Status: COMPLETED ·Phase: PHASE3
-
Vaccination With Autologous Breast Cancer Cells Engineered to Secrete Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Metastatic Breast Cancer Patients
NCT00317603 ·Status: COMPLETED ·Phase: PHASE1
-
Paclitaxel Plus Monoclonal Antibody Therapy in Treating Women With Recurrent or Metastatic Breast Cancer
NCT00003539 ·Status: COMPLETED ·Phase: PHASE2
-
Pyrazoloacridine in Treating Women With Metastatic Breast Cancer
NCT00002585 ·Status: COMPLETED ·Phase: PHASE2
-
Bevacizumab With or Without Cyclophosphamide and Methotrexate: A Pilot Study in Women With Operable Breast Cancer
NCT00121134 ·Status: COMPLETED ·Phase: NA
-
Capecitabine in Treating Patients With Metastatic Breast Cancer
NCT00274768 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody Therapy, Cyclosporine, and Paclitaxel in Treating Patients With Recurrent or Refractory Metastatic Breast Cancer
NCT00009763 ·Status: UNKNOWN ·Phase: PHASE1
-
Irinotecan in Treating Patients With Refractory Metastatic Breast Cancer
NCT00003351 ·Status: COMPLETED ·Phase: PHASE2
-
Medroxyprogesterone +/- Cyclophosphamide & Methotrexate in Hormone Receptor-Negative Recurrent/Metastatic Breast Cancer
NCT00577122 ·Status: COMPLETED ·Phase: PHASE2
-
T-Cell Therapy for Advanced Breast Cancer
NCT02792114 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Mitoxantrone With or Without Docetaxel in Treating Women With Metastatic Breast Cancer
NCT00002544 ·Status: COMPLETED ·Phase: PHASE3
-
Capecitabine and Paclitaxel in Treating Patients With Metastatic Breast Cancer
NCT00031876 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Ixabepilone in Treating Patients With Locally Advanced or Metastatic Breast Cancer
NCT00045097 ·Status: COMPLETED ·Phase: PHASE2