Radiation Therapy in Treating Patients With Bile Duct, Gallbladder, or Pancreatic Cancer
NCT00003411 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2016-01-18
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Motexafin gadolinium may increase the effectiveness of radiation therapy by making tumor cells more sensitive to treatment.
PURPOSE: Phase I trial to study the effectiveness of radiation therapy plus motexafin gadolinium in treating patients with bile duct, gallbladder, or pancreatic cancer that cannot be removed surgically.
Conditions
- Extrahepatic Bile Duct Cancer
- Gallbladder Cancer
- Pancreatic Cancer
Interventions
- DRUG
-
motexafin gadolinium
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Pittsburgh
lead OTHER
Principal Investigators
-
Ramesh K. Ramanathan, MD · University of Pittsburgh
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-11-30
- Primary Completion
- 2002-06-30
- Completion
- 2002-06-30
Countries
- United States
Study Locations
More Related Trials
-
Gemcitabine Plus Radiation Therapy in Treating Patients With Pancreatic Cancer
NCT00003546 ·Status: COMPLETED ·Phase: PHASE2
-
Photodynamic Therapy in Treating Patients With Cancer of the Bile Duct, Gallbladder, or Pancreas
NCT00003923 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine Plus Radiation Therapy in Treating Patients With Pancreatic Cancer
NCT00003426 ·Status: COMPLETED ·Phase: PHASE1
-
High or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and Nab-paclitaxel in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery
NCT01921751 ·Status: TERMINATED ·Phase: PHASE2
-
Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
NCT04172532 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
NCT06958328 ·Status: RECRUITING ·Phase: PHASE3
-
Study of Amplitude-Modulated Radiofrequency Electromagnetic Fields in Metastatic Pancreatic Cancer
NCT05776524 ·Status: RECRUITING ·Phase: PHASE2
-
Pemetrexed, Gemcitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer
NCT00310050 ·Status: TERMINATED ·Phase: PHASE1
-
PhI Study of Erbitux & Gemcitabine w/Radiation Therapy for Locally Adv. Pancreas Ca
NCT00467116 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Pancreatic Cancer
NCT00026403 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Gemcitabine, Docetaxel, and Capecitabine in Combination With Stereotactic Radiosurgery
NCT00833859 ·Status: TERMINATED ·Phase: PHASE2
-
Radiation Therapy Plus Chemotherapy in Treating Patients With Pancreatic Cancer
NCT00002689 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Intra-Arterial and Intra-Tumoral Ad-p53 With Capecitabine (Xeloda) or Anti-PD-1 in Liver Metastases of Solid Tumors and Recurrent Head and Neck Squamous Cell Cancer
NCT02842125 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors
NCT05799274 ·Status: RECRUITING ·Phase: PHASE1
-
Radiotherapy for Locally Advanced Pancreatic Carcinomas (Phase II Trial)
NCT05191940 ·Status: RECRUITING ·Phase: NA
-
Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma
NCT07126158 ·Status: RECRUITING ·Phase: PHASE2
-
Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer
NCT03073785 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Gemcitabine and Nab-paclitaxel Combined With Momelotinib in Participants With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma
NCT02101021 ·Status: TERMINATED ·Phase: PHASE3
-
Radiation Therapy and Chemotherapy in Treating Patients With Cancer of the Pancreas or Stomach
NCT00003157 ·Status: COMPLETED ·Phase: PHASE1
-
Use of High-dose Radiation Therapy Plus Chemotherapy to Improve the Likelihood of Surgical Treatment in Patients With Locally Advanced Pancreatic Cancer
NCT03523312 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Gemcitabine and Radiation Therapy in Treating Patients With Cancer of the Pancreas
NCT00010166 ·Status: COMPLETED ·Phase: PHASE2
-
MP0317 in Combination With Chemoimmunotherapy in First Line Treatment for Patients With Advanced Biliary Tract Carcinoma
NCT07036380 ·Status: RECRUITING ·Phase: PHASE2
-
Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer
NCT03203525 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Stereotactic Body Radiotherapy Combined With PD-1 Blockers for Locally Advanced or Locally Recurrent Pancreatic Cancer
NCT06195254 ·Status: COMPLETED
-
Pilot Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in Combination With GC4419 in Pancreatic Cancer
NCT03340974 ·Status: COMPLETED ·Phase: PHASE1/PHASE2