Irinotecan in Treating Patients With Solid Tumors or Lymphoma Who Have Abnormal Liver or Kidney Function or Who Have Received Radiation Therapy to the Pelvis
NCT00003368 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2013-03-21
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Irinotecan may be effective in treating patients with abnormal liver or kidney function or who have received radiation therapy.
PURPOSE: Phase I trial to study the effectiveness of irinotecan in treating patients with solid tumors or lymphoma who have abnormal liver or kidney function or who have had previous radiation therapy to the pelvis.
Conditions
- Lymphoma
- Small Intestine Cancer
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
irinotecan hydrochloride
Sponsors & Collaborators
-
Alliance for Clinical Trials in Oncology
collaborator OTHER -
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Alan P. Venook, MD · University of California, San Francisco
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-06-30
- Completion
- 2006-07-31
Countries
- United States
Study Locations
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