Rituximab Plus Interleukin-2 in Treating Patients With Lymphoma
NCT00003356 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 58
Last updated 2013-10-16
Summary
RATIONALE: Monoclonal antibodies can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Interleukin-2 may stimulate a person's white blood cells to kill cancer cells.
PURPOSE: Phase I/II trial to study the effectiveness of combining rituximab and interleukin-2 intreating patients who have low-grade mantle cell lymphoma or follicular lymphoma.
Conditions
Interventions
- BIOLOGICAL
-
aldesleukin
- BIOLOGICAL
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Rochester
lead OTHER
Principal Investigators
-
Joseph D. Rosenblatt, MD · University of Miami Sylvester Comprehensive Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1997-11-30
- Primary Completion
- 2002-05-31
- Completion
- 2002-05-31
Countries
- United States
Study Locations
More Related Trials
-
Interleukin-12 Plus Rituximab in Treating Patients With Non-Hodgkin's Lymphoma
NCT00004260 ·Status: COMPLETED ·Phase: PHASE1
-
Rituximab, Lenalidomide, and Ibrutinib in Treating Patients With Previously Untreated Stage II-IV Follicular Lymphoma
NCT01829568 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Waldenstrom's Macroglobulinemia
NCT00060346 ·Status: TERMINATED ·Phase: PHASE2
-
Rituximab Plus Cyclophosphamide in Treating Patients With Indolent Stage III or Stage IV Non-Hodgkin's Lymphoma
NCT00003605 ·Status: WITHDRAWN ·Phase: PHASE2
-
Rituximab and GM-CSF in Treating Patients With Newly Diagnosed Follicular B-Cell Lymphoma
NCT00411086 ·Status: COMPLETED ·Phase: PHASE2
-
High Dose Rituximab for Initial Treatment of Indolent B-Cell Lymphomas
NCT00895661 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy Study of Immunotherapy With Rituximab and Interleukin-2 in Patients With Non-Hodgkin's Lymphoma
NCT00994643 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Recombinant Interleukin 21 in Combination With Rituxan for Non-Hodgkin's Lymphoma
NCT00347971 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Therapy and Rituximab in Treating Patients With Stage I-II Grade 1 or Grade 2 Follicular Lymphoma
NCT01473628 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Monoclonal Antibody Plus Interleukin-2 in Treating Patients With Leukemia or Lymphoma
NCT00002681 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Rituximab in Treating Patients With Follicular Non-Hodgkin's Lymphoma
NCT00227695 ·Status: COMPLETED ·Phase: PHASE3
-
Rituximab Plus Fludarabine in Treating Patients With Waldenstrom's Macroglobulinemia
NCT00020800 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab in Treating Patients With Waldenstrom's Macroglobulinemia
NCT00005609 ·Status: COMPLETED ·Phase: PHASE2
-
Irradiated Donor Lymphocytes and Rituximab in Treating Patients With Relapsed or Refractory Lymphoproliferative Disease
NCT00176475 ·Status: TERMINATED ·Phase: PHASE1
-
Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
NCT07225439 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
A Phase II Trial of Alemtuzumab and Rituximab in Patients With Previously Untreated CLL
NCT00858117 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab Followed by Combination Chemotherapy in Treating Patients With Refractory or Recurrent Non-Hodgkin's Lymphoma
NCT00006669 ·Status: WITHDRAWN ·Phase: PHASE2
-
Radiolabeled Monoclonal Antibody Plus Rituximab With and Without Filgrastim and Interleukin-11 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
NCT00012298 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Epcoritamab and Rituximab for First-line Follicular Lymphoma
NCT05783609 ·Status: RECRUITING ·Phase: PHASE2
-
Rituximab and Denileukin Diftitox in Treating Patients With Previously Untreated Stage III or Stage IV Follicular B-Cell Non-Hodgkin's Lymphoma
NCT00460109 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy and Rituximab in Treating Patients With Untreated Mantle Cell Lymphoma
NCT00433537 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab, Cyclophosphamide, and G-CSF Followed By Combination Chemotherapy in Treating Patients Who Are Undergoing Autologous Stem Cell Transplant Followed By Rituximab and GM-CSF for Refractory Diffuse Large B-Cell Lymphoma
NCT00242996 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab and Liposomal Doxorubicin in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
NCT00244985 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Rituximab in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease
NCT00003849 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Large Cell Lymphoma
NCT00005631 ·Status: COMPLETED ·Phase: PHASE2