EF5 in Treating Patients With Solid Tumors
NCT00003282 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2013-01-16
Summary
Diagnostic procedures using the drug EF5 to detect the presence of oxygen in tumor cells may help to plan effective treatment for solid tumors. This phase I trial is studying how well EF5 works in detecting the presence of oxygen in tumor cells in patients with solid tumors that can be biopsied or removed by surgery
Conditions
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
EF5
Given IV
- PROCEDURE
-
therapeutic conventional surgery
Undergo resection
- PROCEDURE
-
biopsy
Undergo biopsy
- OTHER
-
pharmacological study
Correlative studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Stephen Michael Hahn · Abramson Cancer Center at Penn Medicine
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-03-31
- Primary Completion
- 2005-05-31
Countries
- United States
Study Locations
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