Interleukin-12 in Treating Patients With Multiple Myeloma
NCT00003149 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2013-06-21
Summary
RATIONALE: Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a person's blood cells to kill multiple myeloma cells.
PURPOSE: Randomized phase II trial to compare the effectiveness of interleukin-12 given at different times in treating patients with multiple myeloma.
Conditions
- Multiple Myeloma and Plasma Cell Neoplasm
Interventions
- BIOLOGICAL
-
recombinant interleukin-12
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Eastern Cooperative Oncology Group
lead NETWORK
Principal Investigators
-
Martha Q. Lacy, MD · Mayo Clinic
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1997-12-31
- Completion
- 2006-09-30
Countries
- United States
Study Locations
More Related Trials
-
Vaccine Therapy With or Without Interleukin-12 in Treating Patients With Stage III or Stage IV Melanoma
NCT00003339 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019448 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-2 Plus Monoclonal Antibody Therapy in Treating Patients With Solid Tumors
NCT00002994 ·Status: COMPLETED ·Phase: PHASE1
-
Cell Therapy for Metastatic Melanoma Using CD8 Enriched Tumor Infiltrating Lymphocytes
NCT01236573 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Interleukin-12 in Treating Patients With Metastatic or Recurrent Breast Cancer
NCT00004893 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-12 Plus Interleukin-2 in Treating Patients With Advanced Solid Tumors
NCT00005604 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Using Tumor-Reactive Autologous Tumor Infiltrating Lymphocytes (TIL) in Metastatic Melanomas
NCT02375984 ·Status: TERMINATED ·Phase: PHASE2
-
Interleukin-12 in Treating Patients With Cancer in the Abdomen
NCT00003046 ·Status: COMPLETED ·Phase: PHASE1
-
A Pilot Study Using Short-Term Cultured Anti-Tumor Autologous Lymphocytes
NCT03526185 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Xcellerated T CellsTM in Patients With Multiple Myeloma
NCT00078065 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00002845 ·Status: UNKNOWN ·Phase: PHASE2
-
Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma
NCT00019188 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma
NCT01993719 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy With or Without Recombinant Interleukin-12 Followed by Daclizumab in Treating Patients With Metastatic Melanoma
NCT01307618 ·Status: TERMINATED ·Phase: PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019487 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019721 ·Status: COMPLETED ·Phase: PHASE2
-
Interleukin-12 Followed by Interferon Alfa in Treating Patients With Advanced Cancer
NCT00003451 ·Status: COMPLETED ·Phase: PHASE1
-
Liposomal Doxorubicin and Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma
NCT00020449 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy Plus Interleukin-2 With or Without Interferon Alfa-2b in Treating Patients With Stage III Melanoma
NCT00004104 ·Status: COMPLETED ·Phase: PHASE2
-
Ph I/II Trial of Cord Blood-derived NK Cells With NY-ESO-1 TCR/IL-15 for R/R Myeloma
NCT06066359 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Interleukin-21 in Treating Patients With Metastatic or Recurrent Malignant Melanoma
NCT00514085 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Multiple Myeloma
NCT00019097 ·Status: COMPLETED ·Phase: PHASE2
-
Lymphocyte-Depleting Nonmyeloablative Preparative Chemotherapy Followed By Autologous Lymphocyte Infusion, Peptide Vaccine Plus Montanide ISA-51, and Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00079144 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Therapy of Interleukin-12 and Interleukin-2 to Treat Advanced Cancer
NCT00005655 ·Status: TERMINATED ·Phase: PHASE1
-
Vaccine Therapy and Interleukin-12 in Treating Patients With Metastatic Melanoma
NCT00002952 ·Status: COMPLETED ·Phase: PHASE1/PHASE2