A Study of 141W94 in Combination With Other Anti-HIV Drugs
NCT00002372 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2005-06-24
Summary
To determine the steady-state pharmacokinetics of 141W94 in combination with saquinavir, indinavir and nelfinavir after multiple oral dosing. To determine the steady-state pharmacokinetics of saquinavir, indinavir, and nelfinavir in combination with 141W94 after multiple oral dosing. To assess the safety and tolerability of multiple doses of 141W94 when combined with saquinavir, indinavir and nelfinavir.
Conditions
- HIV Infections
Interventions
- DRUG
-
Indinavir sulfate
- DRUG
-
Amprenavir
- DRUG
-
Nelfinavir mesylate
- DRUG
-
Saquinavir
Sponsors & Collaborators
-
Glaxo Wellcome
lead INDUSTRY
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
More Related Trials
-
A Study of Retrovir and Epivir Alone or in Combination With 141W94 in HIV-Infected Patients
NCT00002195 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations
NCT00002430 ·Status: COMPLETED ·Phase: NA
-
A Study of an Investigational Regimen Combining FDA Approved HIV Drugs in HIV-Infected Subjects
NCT00363142 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of 1592U89 in Combination With Protease Inhibitors in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
NCT00002440 ·Status: COMPLETED ·Phase: PHASE2
-
A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Early Asymptomatic HIV Infection
NCT00002176 ·Status: COMPLETED ·Phase: NA
-
Safety and Effectiveness of Giving Combinations of Three or Four Anti-HIV Drugs to HIV-Infected Patients
NCT00002211 ·Status: COMPLETED ·Phase: NA
-
The Safety and Effectiveness of Nevirapine Plus Nelfinavir in HIV-1 Infected Patients Who Have Taken Stavudine
NCT00002381 ·Status: COMPLETED ·Phase: PHASE1
-
Five-Drug Anti-HIV Treatment Followed by Treatment Interruption in Patients Who Have Recently Been Infected With HIV
NCT00000940 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of 141W94 Used Alone or in Combination With Zidovudine Plus 3TC in HIV-Infected Patients
NCT00001085 ·Status: COMPLETED ·Phase: PHASE2
-
A Randomized, Parallel Arm, Comparative, Open Label, Multicenter Study of the Activity and Safety of Two Formulations of Saquinavir in Combination With Other Antiretroviral Drugs
NCT00002162 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Combivir Plus Abacavir Plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs
NCT00002217 ·Status: COMPLETED ·Phase: NA
-
A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Recent HIV Infection
NCT00002177 ·Status: COMPLETED ·Phase: NA
-
Safety and Effectiveness of an Anti-HIV Drug Combination Taken Twice Daily
NCT00002241 ·Status: UNKNOWN ·Phase: PHASE2
-
The Safety and Effectiveness of Retrovir Plus HIVID Combined With Either Nevirapine or Invirase in the Treatment of HIV Infection
NCT00002347 ·Status: COMPLETED ·Phase: PHASE2
-
The Safety and Effectiveness of Two Forms of Saquinavir Combined With Other Anti-HIV Drugs in HIV-Infected Infants and Children
NCT00002380 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Optimisation of Stavudine for the Treatment of HIV Infection
NCT02670772 ·Status: COMPLETED ·Phase: PHASE3
-
The Safety and Effectiveness of 1592U89 Plus 141W94 Plus DMP 266 in Patients With HIV Who Developed a Resistance to Protease Inhibitors
NCT00002213 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Effectiveness of Giving Indinavir and Nelfinavir to HIV-Infected Patients
NCT00002375 ·Status: COMPLETED ·Phase: NA
-
Safety and Effectiveness of Adding PMPA Prodrug to an Anti-HIV Drug Combination to Treat HIV-Infected Patients
NCT00002415 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Effectiveness of Giving Two Nucleoside Reverse Transcriptase Inhibitors Alone or in Combination With 141W94 to HIV-Infected Children Who Have Never Received Protease Inhibitors
NCT00002193 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Three Drug Combination Therapies in HIV-Infected Patients Who Have Never Been Treated With Anti-HIV Drugs
NCT00002407 ·Status: COMPLETED ·Phase: NA
-
A Comparison of Two Dose Levels of Indinavir Combined With Two Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs) in HIV-Infected Patients
NCT00002406 ·Status: COMPLETED ·Phase: PHASE3
-
A Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients
NCT00005106 ·Status: COMPLETED ·Phase: PHASE4
-
A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected Patient
NCT00002184 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Effectiveness of 3 Anti-HIV Treatments in Patients Who Have Failed Previous Treatments Containing Nelfinavir
NCT00006326 ·Status: TERMINATED ·Phase: NA