An Ascending, Single Oral Dose Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects
NCT00002271 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL
Last updated 2005-06-24
Summary
To characterize the pharmacokinetics of orally administered 3'-deoxy-3'-fluorothymidine (FLT), in a liquid formulation, after single doses in asymptomatic HIV-infected patients and to assess the safety and tolerance of the single oral doses of FLT.
Conditions
- HIV Infections
Interventions
- DRUG
-
Alovudine
Sponsors & Collaborators
-
Lederle Laboratories
lead INDUSTRY
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
More Related Trials
-
A Study To Investigate The Clearance Of PF-04776548 From The Body Following A Very Low (Micro) Dose Of The Compound Using A Low Level Of Radiotracer To Help Quantify Expected Low Concentrations Of PF-04776548 In The Body
NCT01045317 ·Status: COMPLETED ·Phase: PHASE1
-
The Safety and Effectiveness of U-90152 in HIV-1 Infected Patients Who Take Zidovudine
NCT00002312 ·Status: COMPLETED ·Phase: NA
-
Study of the Absorption, Metabolism, and Route of Elimination of a Novel Class of Anti-HIV 1 Drugs (BMS-955176) in Humans.
NCT02206711 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 2 Study Of PF-00232798 In HIV Positive Patients
NCT00495677 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Azidothymidine Plus Methadone in Patients With AIDS and AIDS Related Complex (ARC)
NCT00001008 ·Status: COMPLETED ·Phase: NA
-
A Phase I Evaluation of Azidothymidine (AZT) in Children With Acquired Immune Deficiency Syndrome (AIDS) or AIDS Related Complex (ARC)
NCT00000701 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Trial of Alternating and Intermittent Regimens of 2',3'-Dideoxycytidine and 3'-Azido-3'-Deoxythymidine in the Treatment of Patients With AIDS and Advanced ARC
NCT00000718 ·Status: COMPLETED ·Phase: NA
-
A Study of Zidovudine in HIV-Infected Patients With Liver Disease
NCT00001001 ·Status: COMPLETED ·Phase: NA
-
A Phase I, Dose-Escalating Safety and Tolerance Study of sCD4-PE40 in HIV-Infected Persons
NCT00000743 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Zidovudine for Asymptomatic HIV-Infected Individuals
NCT00000736 ·Status: COMPLETED ·Phase: PHASE3
-
A Safety, Pilot Pharmacokinetics and Neurocognitive Study of AS-101 in Combination With Zidovudine in AIDS/ARC Patients
NCT00002013 ·Status: COMPLETED ·Phase: NA
-
The Safety and Effectiveness of Zidovudine in the Treatment of Patients With Early AIDS Related Complex
NCT00001011 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of the Changes in HIV-1 Burden in Peripheral Blood and Lymphoid Tissue Following Zidovudine ( AZT ) Treatment in HIV-1-Infected Patients With CD4+ Cells Between 100 and 500 Cells/mm3.
NCT00000818 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Effectiveness of the Drug DPC 083 in Combination With Nucleoside Analogue Reverse Transcriptase Inhibitors in HIV-1-Infected Patients Who Are Failing Treatment With Nonnucleoside Reverse Transcriptase Inhibitors
NCT00007449 ·Status: UNKNOWN ·Phase: PHASE2
-
A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV Infection
NCT00002117 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of AMD11070 in HIV-infected Patients Carrying X4-tropic Virus
NCT00361101 ·Status: COMPLETED ·Phase: PHASE1
-
A Trial of Alternating 2',3'-Dideoxycytidine and Zidovudine in the Treatment of Patients With Advanced HIV Disease
NCT00000719 ·Status: COMPLETED ·Phase: NA
-
A Clinical Study of the Interactions Between Azvudine Tablets (FNC) and Rifampicin Capsules (RIF)
NCT07002255 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients
NCT00000991 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Dideoxycytidine Plus Zidovudine (AZT) in HIV-Infected Children Who Have Taken AZT
NCT00001032 ·Status: COMPLETED ·Phase: PHASE2
-
First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4011499 in Healthy Participants
NCT05393271 ·Status: COMPLETED ·Phase: PHASE1
-
The Safety and Effectiveness of Zidovudine (AZT) in the Treatment of HIV Infection in Patients With AIDS and Advanced ARC
NCT00000999 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of the Interaction Between High Dose Sulfamethoxazole/Trimethoprim and Zidovudine
NCT00000734 ·Status: COMPLETED ·Phase: NA
-
Study of Itraconazole in Patients With Advanced HIV Infection
NCT00002370 ·Status: COMPLETED ·Phase: NA
-
A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease
NCT00002033 ·Status: COMPLETED ·Phase: NA