A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients
NCT00002000 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL
Last updated 2005-06-24
Summary
To evaluate the safety and efficacy of oral valacyclovir hydrochloride (256U87) vs. acyclovir in the treatment of recurrent anogenital herpes in HIV-infected patients (CD4 greater than or equal to 100).
Conditions
- Herpes Simplex
- HIV Infections
Interventions
- DRUG
-
Valacyclovir hydrochloride
- DRUG
-
Acyclovir
Sponsors & Collaborators
-
Glaxo Wellcome
lead INDUSTRY
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 13 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
More Related Trials
-
Randomized Trial to Evaluate Suppressive Effect of High-Dose Acyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2
NCT00362297 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Famciclovir 1-day Treatment Compared to 3-day Treatment With Valacyclovir in Adults With Recurrent Genital Herpes
NCT00306787 ·Status: COMPLETED ·Phase: PHASE3
-
Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV
NCT00527618 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Valacyclovir Hydrochloride in the Prevention of Life-Threatening Cytomegalovirus Disease in HIV-Infected Patients
NCT00001038 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Valacyclovir in the Reduction of HSV-2 Recurrence and Shedding
NCT00803543 ·Status: COMPLETED ·Phase: NA
-
A Study With ASP2151 in Subjects With Recurrent Episodes of Genital Herpes
NCT00486200 ·Status: COMPLETED ·Phase: PHASE2
-
The Safety and Effectiveness of Valacyclovir HCl in the Treatment of Herpes Simplex or Varicella/Zoster Infections in HIV-1 Infected Children
NCT00001054 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study of Valacyclovir to Suppress HSV and HIV Shedding in Coinfected Persons
NCT00161434 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the Blood
NCT00001115 ·Status: COMPLETED ·Phase: NA
-
A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes
NCT00076232 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluating Three Grams Daily Valacyclovir in Patients With Chronic Hepatitis C and HSV-2 Infection (Phase I)
NCT01453075 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy Study for a New Antiviral Drug to Treat Genital Herpes Type 2
NCT01047540 ·Status: COMPLETED ·Phase: PHASE2
-
Can Valacyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals?
NCT00860977 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy Comparator Trial of a New Drug Against Genital Herpes
NCT01658826 ·Status: TERMINATED ·Phase: PHASE2
-
An Open-label Trial of the Effect of Valacyclovir on Plasma HIV-1 Levels Among HIV-1 Seropositive and HSV-1/2 Seronegative Persons
NCT01059084 ·Status: WITHDRAWN ·Phase: NA
-
Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2?
NCT01176409 ·Status: COMPLETED ·Phase: PHASE3
-
Valacyclovir vs. Acyclovir as HSV-2 Suppressive Therapy: Effect on Plasma HIV-1 Levels Among HIV-1/HSV-2 Co-infected Persons
NCT01026454 ·Status: COMPLETED ·Phase: PHASE4
-
A Randomized Trial to Evaluated the Suppressive Effect of Acyclovir on Rapidly Cleared HSV-2 Reactivation
NCT00723229 ·Status: COMPLETED ·Phase: PHASE4
-
VALTREX(Valacyclovir) Once Daily for Viral Shedding In Subjects Newly Diagnosed With HSV-2
NCT00306293 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of FV-100 Versus Valacyclovir in Patients With Herpes Zoster
NCT00900783 ·Status: COMPLETED ·Phase: PHASE2
-
Patient-initiated Episodic Treatment of Recurrent Genital Herpes in Black Patients
NCT00477334 ·Status: COMPLETED ·Phase: PHASE4
-
Randomized Trial to Evaluate Suppressive Effect of High-Dose Valacyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2
NCT01346475 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Vacyless® Versus Valtrex® in Patients With Herpes Zoster
NCT02152800 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Oral Famciclovir in Patients With Active Recurrent Genital Herpes
NCT00171990 ·Status: COMPLETED ·Phase: PHASE3
-
Randomized Study of Two Doses of Oral Valacyclovir in Immunocompromised Patients With Uncomplicated Herpes Zoster
NCT00006131 ·Status: COMPLETED ·Phase: NA