Trial to Reduce Alloimmunization to Platelets (TRAP)
NCT00000589 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL
Last updated 2016-11-07
Summary
To determine the best, clinically useful procedure to prevent or minimize platelet alloimmunization as a cause of refractoriness to platelet transfusion in patients undergoing marrow ablative chemotherapy for acute myelogenous leukemia.
Conditions
- Blood Platelets
- Hematologic Diseases
- Immunization
- Leukemia, Myelocytic, Acute
- Blood Transfusion
Interventions
- PROCEDURE
-
platelet transfusion
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
lead NIH
Principal Investigators
-
Hayden Braine · Johns Hopkins University
-
Kuo-Jang Kao · University of Florida
-
Jeffrey McCullough · University of Minnesota
-
Janice McFarland · Blood Center of Southeastern Wisconsin
-
Charles Schiffer · University of Maryland
-
Sherrill Schlichter · Bloodworks
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
Eligibility
- Min Age
- 15 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1989-08-31
- Completion
- 1997-07-31
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