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Effects of Alcohol History on Effects of Nitrous Oxide - 9

NCT00000257 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19

Last updated 2015-05-28

No results posted yet for this study

Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To determine effects of alcohol history on the reinforcing, subjective and psychomotor effects of nitrous oxide in healthy volunteers.

Conditions

  • Alcohol-Related Disorders
  • Opioid-Related Disorders
  • Substance-Related Disorders

Interventions

DRUG

0% N2O and 10% N2O

DRUG

0% N2O and 20% N2O

DRUG

0% N2O and 30% N2O

DRUG

0% N2O and 40% N2O

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • University of Chicago

    lead OTHER

Principal Investigators

  • James Zacny, Ph.D. · University of Chicago

Study Design

Allocation
NON_RANDOMIZED
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
37 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1995-09-30
Primary Completion
1997-04-30
Completion
1997-04-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00000257 on ClinicalTrials.gov