Effects of Subanesthetic Concentrations of Nitrous Oxide - 1

NCT00000249 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2015-05-28

No results posted yet for this study

Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To examine effects of subanesthetic concentrations of nitrous oxide on cold-pressor pain in humans.

Conditions

  • Opioid-Related Disorders
  • Substance-Related Disorders

Interventions

DRUG

20% N2O

20% inhaled N2O

DRUG

30% N2O

30% inhaled N2O

DRUG

40% N2O

40% inhaled N2O

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH
  • University of Chicago

    lead OTHER

Principal Investigators

  • James Zacny, Ph.D. · University of Chicago

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
37 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1993-09-30
Primary Completion
1995-06-30
Completion
1995-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00000249 on ClinicalTrials.gov