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Oral Semaglutide Absorption Enhancer SNAC Linked to Gut Microbiota Changes in Animal Study

Mar 01, 2026

Researchers at Adelaide University found that salcaprozate sodium (SNAC), used in oral semaglutide formulations, was associated with gut bacteria changes, elevated inflammatory markers, and reduced brain-derived protein levels in a 21-day animal study.

Oral Semaglutide Absorption Enhancer SNAC Linked to Gut Changes in Animal Study

Feb 18, 2026

A University of South Australia study finds salcaprozate sodium (SNAC), the compound enabling oral semaglutide tablets to work, may alter gut bacteria and increase inflammatory markers in rats, though human effects remain unclear.