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Jul 02, 2026
Recent studies applied HPLC-QTOF-MS/MS and LC-MS/MS to profile lichen metabolites, optimize CYP assay buffer conditions, and quantify tramadol and dexketoprofen in rat plasma, expanding the scope of pharmaceutical analysis.
Apr 01, 2026
A self-reinforcing ROS-generating nanodrug and a modular ferritin-based LYTAC platform represent two new nanoparticle strategies for tumor-targeted therapy, with high drug loading, efficient protein degradation, and tumor growth inhibition in vivo.
May 11, 2026
Two studies reported mitochondrial mechanisms linked to diabetic wound repair, including targeted mitochondrial transplantation and the circular RNA circMTRNR2. The findings showed improved healing in experimental models and identified potential targets for chronic wound treatment.
Apr 24, 2026
A preclinical study in Precision Clinical Medicine found that luteolin and astragaloside IV improved recovery after severe spinal cord injury in cell and rat models. The combined treatment reduced oxidative stress and neuroinflammation and improved motor function over five weeks.
Apr 02, 2026
A February 2026 review analyzes strategies for kidney-targeted drug delivery systems, examining renal targeting mechanisms and nanocarrier platforms. The review highlights how functionalized nanoparticles can achieve enhanced renal specificity while addressing remaining translational challenges in the field.
