News Related to Mitochondrial Function

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CRISPR Gene Editing Advances in Heart Failure, Cystic Fibrosis, and Cholesterol Treatment

Mar 09, 2026

Three new CRISPR-based therapies show promise for treating heart failure through mitochondrial enhancement, cystic fibrosis via lipid nanoparticle gene insertion, and elevated cholesterol with single-dose gene editing targeting ANGPTL3.

Klothea Bio Launches Phase 1b Trial of Alpha Klotho mRNA Therapy for Lifespan Extension

Feb 27, 2026

Klothea Bio has initiated a Phase 1b clinical trial of AKL003, an alpha Klotho mRNA therapeutic designed to extend human lifespan. The randomized, placebo-controlled study is enrolling 21 healthy adults in Prospera, Honduras.