News Related to Major Pathological Response

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Studies Link Dynamic ctDNA Monitoring to Treatment Response in Gastroesophageal and Rectal Cancers

Apr 19, 2026

Studies in gastroesophageal and locally advanced rectal cancers linked dynamic ctDNA monitoring to treatment response and prognosis. MRD clearance, more than 90% ctDNA declines, and early ctDNA clearance were associated with better outcomes.

Chemoimmunotherapy Shows Higher Pathologic Response in Head and Neck Cancer

Mar 13, 2026

Meta-analysis of 23 trials finds neoadjuvant chemoimmunotherapy achieved 66% major pathologic response in head and neck cancer patients compared to 18% for dual-agent and 6% for single-agent immunotherapy, though survival impact remains unclear.