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Semaglutide Shows Promise for Osteoarthritis While SNAC Ingredient Raises Safety Questions

Feb 21, 2026

New research reveals semaglutide may directly repair cartilage in osteoarthritis patients, while a separate study raises concerns about SNAC, an ingredient used in oral semaglutide formulations, and its effects on gut health.

Oral Semaglutide Absorption Enhancer SNAC Linked to Gut Changes in Animal Study

Feb 18, 2026

A University of South Australia study finds salcaprozate sodium (SNAC), the compound enabling oral semaglutide tablets to work, may alter gut bacteria and increase inflammatory markers in rats, though human effects remain unclear.