A study in Life Metabolism shows that a single post-meal blood biomarker, 1-hour postprandial SPARC, predicts who benefits most from a Mediterranean diet. Lower baseline SPARC-1H levels were linked to greater improvements in insulin resistance and glucose control in a six-month trial.
Scientists have developed a new transcriptomic clock that predicts biological age and mortality using gene activity patterns conserved across species. Longevity experts also recommend tracking specific biomarkers like fasting glucose, ApoB, and hs-CRP with optimal ranges to monitor health proactively. Regular biomarker testing from mid-30s onwards is encouraged for early detection of age-related changes.
Evidence on ketogenic diets remains limited for psychiatric disorders and diabetes, while a systematic review in overweight and obese women with PCOS found significant short-term improvements. Experts said more controlled, long-term studies are needed.
